A new experimental platform facilitates assessment of the transcriptional and chromatin landscapes of aging yeast

Replicative aging of Saccharomyces cerevisiae is an established model system for eukaryotic cellular aging.A limitation in yeast lifespan studies has been the difficulty of separating old cells from young cells in large quantities.We engineered a new platform, the Miniature-chemostat Aging Device (MAD), that enables purification of aged cells at su

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Assessment of the degree of social harmfulness of acts exhausting the elements set out in Article 35(1)-(2) of the Act of 21 August 1997 on the protection of animals. Comments on the background of rulings by common courts and the Supreme Court

The views expressed in the public discourse, accusing the courts of excessive leniency towards the perpetrators of crimes against animals, as well as the problems that the courts often have in correctly determining the degree of social harmfulness of the assessed criminal acts, made it reasonable to devote this article to the title issue.After all,

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Leiomyosarcoma of the inferior vena cava level II involvement: curative resection and reconstruction of renal veins

Abstract Leiomyosarcoma of the inferior vena cava (IVCL) is a rare retroperitoneal tumor.We report two cases of level II (middle level, renal veins to hepatic veins) IVCL, who underwent en bloc resection with reconstruction of bilateral or left renal venous return using prosthetic grafts.In our cases, IVCL is documented to be occluded preoperativel

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